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Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations

Internal friction is an important contribution to protein dynamics at all stages along the folding reaction. Even in unfolded and intrinsically disordered proteins, internal friction has a large influence, as demonstrated with several experimental techniques and in simulations. However, these method...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Soranno, Andrea, Holla, Andrea, Dingfelder, Fabian, Nettels, Daniel, Makarov, Dmitrii E., Schuler, Benjamin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347633/
https://ncbi.nlm.nih.gov/pubmed/28223518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616672114
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