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Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS

The properties of unfolded proteins are essential both for the mechanisms of protein folding and for the function of the large group of intrinsically disordered proteins. However, the detailed structural and dynamical characterization of these highly dynamic and conformationally heterogeneous ensemb...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Aznauryan, Mikayel, Delgado, Leonildo, Soranno, Andrea, Nettels, Daniel, Huang, Jie-rong, Labhardt, Alexander M., Grzesiek, Stephan, Schuler, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027429/
https://ncbi.nlm.nih.gov/pubmed/27566405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607193113
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