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High-pressure NMR reveals close similarity between cold and alcohol protein denaturation in ubiquitin
Proteins denature not only at high, but also at low temperature as well as high pressure. These denatured states are not easily accessible for experiment, because usually heat denaturation causes aggregation, whereas cold or pressure denaturation occurs at temperatures well below the freezing point...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562818/ https://ncbi.nlm.nih.gov/pubmed/23284170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212222110 |
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