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Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations

Internal friction is an important contribution to protein dynamics at all stages along the folding reaction. Even in unfolded and intrinsically disordered proteins, internal friction has a large influence, as demonstrated with several experimental techniques and in simulations. However, these method...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Soranno, Andrea, Holla, Andrea, Dingfelder, Fabian, Nettels, Daniel, Makarov, Dmitrii E., Schuler, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347633/
https://ncbi.nlm.nih.gov/pubmed/28223518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616672114
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