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Integrated view of internal friction in unfolded proteins from single-molecule FRET, contact quenching, theory, and simulations

Internal friction is an important contribution to protein dynamics at all stages along the folding reaction. Even in unfolded and intrinsically disordered proteins, internal friction has a large influence, as demonstrated with several experimental techniques and in simulations. However, these method...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Soranno, Andrea, Holla, Andrea, Dingfelder, Fabian, Nettels, Daniel, Makarov, Dmitrii E., Schuler, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347633/
https://ncbi.nlm.nih.gov/pubmed/28223518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616672114
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