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Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy

Internal friction, which reflects the “roughness” of the energy landscape, plays an important role for proteins by modulating the dynamics of their folding and other conformational changes. However, the experimental quantification of internal friction and its contribution to folding dynamics has rem...

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書誌詳細
主要な著者: Soranno, Andrea, Buchli, Brigitte, Nettels, Daniel, Cheng, Ryan R., Müller-Späth, Sonja, Pfeil, Shawn H., Hoffmann, Armin, Lipman, Everett A., Makarov, Dmitrii E., Schuler, Benjamin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497802/
https://ncbi.nlm.nih.gov/pubmed/22492978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117368109
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