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Denoising Single-Molecule FRET Trajectories with Wavelets and Bayesian Inference
A method to denoise single-molecule fluorescence resonance energy (smFRET) trajectories using wavelet detail thresholding and Bayesian inference is presented. Bayesian methods are developed to identify fluorophore photoblinks in the time trajectories. Simulated data are used to quantify the improvem...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Biophysical Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2800976/ https://ncbi.nlm.nih.gov/pubmed/20074517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.047 |
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