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Learning Rates and States from Biophysical Time Series: A Bayesian Approach to Model Selection and Single-Molecule FRET Data

Time series data provided by single-molecule Förster resonance energy transfer (smFRET) experiments offer the opportunity to infer not only model parameters describing molecular complexes, e.g., rate constants, but also information about the model itself, e.g., the number of conformational states. R...

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Detalhes bibliográficos
Main Authors: Bronson, Jonathan E., Fei, Jingyi, Hofman, Jake M., Gonzalez, Ruben L., Wiggins, Chris H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2793368/
https://ncbi.nlm.nih.gov/pubmed/20006957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.031
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