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Empirical Bayes Methods Enable Advanced Population-Level Analyses of Single-Molecule FRET Experiments

Many single-molecule experiments aim to characterize biomolecular processes in terms of kinetic models that specify the rates of transition between conformational states of the biomolecule. Estimation of these rates often requires analysis of a population of molecules, in which the conformational tr...

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Autors principals: van de Meent, Jan-Willem, Bronson, Jonathan E., Wiggins, Chris H., Gonzalez, Ruben L.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985505/
https://ncbi.nlm.nih.gov/pubmed/24655508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.055
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