In Situ Time-Resolved FRET Reveals Effects of Sarcomere Length on Cardiac Thin-Filament Activation

During cardiac thin-filament activation, the N-domain of cardiac troponin C (N-cTnC) binds to Ca(2+) and interacts with the actomyosin inhibitory troponin I (cTnI). The interaction between N-cTnC and cTnI stabilizes the Ca(2+)-induced opening of N-cTnC and is presumed to also destabilize cTnI–actin...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Li, King-Lun, Rieck, Daniel, Solaro, R. John, Dong, Wenji
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2014
Ämnen:
Molecular Machines, Motors and Nanoscale Biophysics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4129473/
https://ncbi.nlm.nih.gov/pubmed/25099807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.05.044
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk