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A Mechanistic Model of Ca Regulation of Thin Filaments in Cardiac Muscle

We present a model of Ca-regulated thin filaments in cardiac muscle where tropomyosin is treated as a continuous elastic chain confined in the closed position on the actin helix by electrostatic forces. The main distinction from previous works is that the intrinsic stress-free helical shape of the t...

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Detalhes bibliográficos
Main Authors: Metalnikova, Nadia A., Tsaturyan, Andrey K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3752105/
https://ncbi.nlm.nih.gov/pubmed/23972846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.06.044
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