The Closed State of the Thin Filament Is Not Occupied in Fully Activated Skeletal Muscle

Muscle contraction is powered by actin-myosin interaction controlled by Ca(2+) via the regulatory proteins troponin (Tn) and tropomyosin (Tpm), which are associated with actin filaments. Tpm forms coiled-coil dimers, which assemble into a helical strand that runs along the whole ∼1 μm length of a th...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Bershitsky, Sergey Y., Koubassova, Natalia A., Ferenczi, Michael A., Kopylova, Galina V., Narayanan, Theyencheri, Tsaturyan, Andrey K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Molecular Machines, Motors, and Nanoscale Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389958/
https://ncbi.nlm.nih.gov/pubmed/28402887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.02.017
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