Three-Dimensional Organization of Troponin on Cardiac Muscle Thin Filaments in the Relaxed State

Muscle contraction is regulated by troponin-tropomyosin, which blocks and unblocks myosin binding sites on actin. To elucidate this regulatory mechanism, the three-dimensional organization of troponin and tropomyosin on the thin filament must be determined. Although tropomyosin is well defined in el...

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Detalhes bibliográficos
Main Authors: Yang, Shixin, Barbu-Tudoran, Lucian, Orzechowski, Marek, Craig, Roger, Trinick, John, White, Howard, Lehman, William
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Molecular Machines, Motors and Nanoscale Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944806/
https://ncbi.nlm.nih.gov/pubmed/24559988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.007
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