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Empirical Bayes Methods Enable Advanced Population-Level Analyses of Single-Molecule FRET Experiments

Many single-molecule experiments aim to characterize biomolecular processes in terms of kinetic models that specify the rates of transition between conformational states of the biomolecule. Estimation of these rates often requires analysis of a population of molecules, in which the conformational tr...

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Detalhes bibliográficos
Main Authors: van de Meent, Jan-Willem, Bronson, Jonathan E., Wiggins, Chris H., Gonzalez, Ruben L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985505/
https://ncbi.nlm.nih.gov/pubmed/24655508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.12.055
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