Conformational Dynamics of Titin PEVK Explored with FRET Spectroscopy

The proline-, glutamate-, valine-, and lysine-rich (PEVK) domain of the giant muscle protein titin is thought to be an intrinsically unstructured random-coil segment. Various observations suggest, however, that the domain may not be completely devoid of internal interactions and structural features....

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Autors principals: Huber, Tamás, Grama, László, Hetényi, Csaba, Schay, Gusztáv, Fülöp, Lívia, Penke, Botond, Kellermayer, Miklós S.Z.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Molecular Machines, Motors, and Nanoscale Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471467/
https://ncbi.nlm.nih.gov/pubmed/23062340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.08.042
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