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Titin Domains Progressively Unfolded by Force Are Homogenously Distributed along the Molecule

Titin is a giant filamentous protein of the muscle sarcomere in which stretch induces the unfolding of its globular domains. However, the mechanisms of how domains are progressively selected for unfolding and which domains eventually unfold have for long been elusive. Based on force-clamp optical tw...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Bianco, Pasquale, Mártonfalvi, Zsolt, Naftz, Katalin, Kőszegi, Dorina, Kellermayer, Miklós
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621543/
https://ncbi.nlm.nih.gov/pubmed/26200869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.002
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