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Titin Domains Progressively Unfolded by Force Are Homogenously Distributed along the Molecule

Titin is a giant filamentous protein of the muscle sarcomere in which stretch induces the unfolding of its globular domains. However, the mechanisms of how domains are progressively selected for unfolding and which domains eventually unfold have for long been elusive. Based on force-clamp optical tw...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Bianco, Pasquale, Mártonfalvi, Zsolt, Naftz, Katalin, Kőszegi, Dorina, Kellermayer, Miklós
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621543/
https://ncbi.nlm.nih.gov/pubmed/26200869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.002
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