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Individual Globular Domains and Domain Unfolding Visualized in Overstretched Titin Molecules with Atomic Force Microscopy

Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin’s globular domains, but the exact structure of the overstretched titin molecule is not known. Here we analyzed, by using high-resolution atomic force microscopy, the structure...

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Autors principals: Mártonfalvi, Zsolt, Kellermayer, Miklós
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896421/
https://ncbi.nlm.nih.gov/pubmed/24465745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085847
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