Stepwise unfolding of titin under force-clamp atomic force microscopy
Here we demonstrate the implementation of a single-molecule force clamp adapted for use with an atomic force microscope. We show that under force-clamp conditions, an engineered titin protein elongates in steps because of the unfolding of its modules and that the waiting times to unfold are exponent...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14610/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11149943/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.021321798 |
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