Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

Diabetes is associated with impaired glucose metabolism in the presence of excess insulin. Glucose and fatty acids provide reducing equivalents to mitochondria to generate energy, and studies have reported mitochondrial dysfunction in type II diabetes patients. If mitochondrial dysfunction can cause...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Morrow, Ryan M., Picard, Martin, Derbeneva, Olga, Leipzig, Jeremy, McManus, Meagan J., Gouspillou, Gilles, Barbat-Artigas, Sébastien, Dos Santos, Carlos, Hepple, Russell T., Murdock, Deborah G., Wallace, Douglas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347565/
https://ncbi.nlm.nih.gov/pubmed/28223503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700997114
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