Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

Diabetes is associated with impaired glucose metabolism in the presence of excess insulin. Glucose and fatty acids provide reducing equivalents to mitochondria to generate energy, and studies have reported mitochondrial dysfunction in type II diabetes patients. If mitochondrial dysfunction can cause...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Morrow, Ryan M., Picard, Martin, Derbeneva, Olga, Leipzig, Jeremy, McManus, Meagan J., Gouspillou, Gilles, Barbat-Artigas, Sébastien, Dos Santos, Carlos, Hepple, Russell T., Murdock, Deborah G., Wallace, Douglas C.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347565/
https://ncbi.nlm.nih.gov/pubmed/28223503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700997114
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