Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

Diabetes is associated with impaired glucose metabolism in the presence of excess insulin. Glucose and fatty acids provide reducing equivalents to mitochondria to generate energy, and studies have reported mitochondrial dysfunction in type II diabetes patients. If mitochondrial dysfunction can cause...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Morrow, Ryan M., Picard, Martin, Derbeneva, Olga, Leipzig, Jeremy, McManus, Meagan J., Gouspillou, Gilles, Barbat-Artigas, Sébastien, Dos Santos, Carlos, Hepple, Russell T., Murdock, Deborah G., Wallace, Douglas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347565/
https://ncbi.nlm.nih.gov/pubmed/28223503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700997114
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