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Role of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in denervation-induced atrophy in aged muscle: facts and hypotheses

Aging-related loss of muscle mass, a biological process named sarcopenia, contributes to mobility impairment, falls, and physical frailty, resulting in an impaired quality of life in older people. In view of the aging of our society, understanding the underlying mechanisms of sarcopenia is a major h...

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Main Authors: Gouspillou, Gilles, Picard, Martin, Godin, Richard, Burelle, Yan, Hepple, Russell T
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922934/
https://ncbi.nlm.nih.gov/pubmed/24472348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-2395-2-13
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