The Role of Peroxisome Proliferator-activated Receptor Gamma Coactivator 1 beta (PGC-1β) in the Pathogenesis of Fructose-Induced Insulin Resistance

Peroxisome proliferator-activated receptor-gamma coactivator 1 beta (PGC-1β) is known to be a transcriptional coactivator for SREBP-1, the master regulator of hepatic lipogenesis. Here we evaluated the role of PGC-1β in the pathogenesis of fructose-induced insulin resistance by using an antisense ol...

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Main Authors: Nagai, Yoshio, Yonemitsu, Shin, Erion, Derek M., Iwasaki, Takanori, Stark, Romana, Weismann, Dirk, Dong, Jianying, Zhang, Dongyan, Jurczak, Michael J., Löffler, Michael G., Cresswell, James, Yu, Xing Xian, Murray, Susan F., Bhanot, Sanjay, Monia, Brett P., Bogan, Jonathan S., Samuel, Varman, Shulman, Gerald I.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131094/
https://ncbi.nlm.nih.gov/pubmed/19254570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2009.01.011
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