cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 2 (CRTC2) Promotes Glucagon Clearance and Hepatic Amino Acid Catabolism to Regulate Glucose Homeostasis

cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) regulates transcription of gluconeogenic genes by specifying targets for the transcription factor CREB in response to glucagon. We used an antisense oligonucleotide directed against CRTC2 in both normal rode...

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Autors principals: Erion, Derek M., Kotas, Maya E., McGlashon, Jacob, Yonemitsu, Shin, Hsiao, Jennifer J., Nagai, Yoshio, Iwasaki, Takanori, Murray, Susan F., Bhanot, Sanjay, Cline, Gary W., Samuel, Varman T., Shulman, Gerald I., Gillum, Matthew P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668772/
https://ncbi.nlm.nih.gov/pubmed/23595987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460246
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