cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 2 (CRTC2) Promotes Glucagon Clearance and Hepatic Amino Acid Catabolism to Regulate Glucose Homeostasis

cAMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) regulates transcription of gluconeogenic genes by specifying targets for the transcription factor CREB in response to glucagon. We used an antisense oligonucleotide directed against CRTC2 in both normal rode...

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Autori principali: Erion, Derek M., Kotas, Maya E., McGlashon, Jacob, Yonemitsu, Shin, Hsiao, Jennifer J., Nagai, Yoshio, Iwasaki, Takanori, Murray, Susan F., Bhanot, Sanjay, Cline, Gary W., Samuel, Varman T., Shulman, Gerald I., Gillum, Matthew P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668772/
https://ncbi.nlm.nih.gov/pubmed/23595987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.460246
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