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Peroxisome Proliferator Activated Receptor-Alpha (PPARα) and PPAR Gamma Coactivator-1alpha (PGC-1α) Regulation of Cardiac Metabolism in Diabetes
Cardiovascular disease is a leading cause of mortality among patients with diabetes, and heart failure exists even in the absence of coronary disease. Myocardial metabolism is altered in the diabetic heart as a result of changes in substrate availability secondary to insulin resistance. The nuclear...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3143064/ https://ncbi.nlm.nih.gov/pubmed/21286700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00246-011-9889-8 |
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