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Role of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) in denervation-induced atrophy in aged muscle: facts and hypotheses

Aging-related loss of muscle mass, a biological process named sarcopenia, contributes to mobility impairment, falls, and physical frailty, resulting in an impaired quality of life in older people. In view of the aging of our society, understanding the underlying mechanisms of sarcopenia is a major h...

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Détails bibliographiques
Auteurs principaux: Gouspillou, Gilles, Picard, Martin, Godin, Richard, Burelle, Yan, Hepple, Russell T
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922934/
https://ncbi.nlm.nih.gov/pubmed/24472348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2046-2395-2-13
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