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SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

Nonsteroidal antiinflammatory drugs (NSAIDs) form a paradigm for the chemoprevention of cancer, preventing colonic tumor progression in both experimental animals and humans. However, the mechanisms underlying the antineoplastic effects of NSAIDs are currently unclear. We found that the mitochondrial...

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Dettagli Bibliografici
Autori principali: Kohli, Manu, Yu, Jian, Seaman, Craig, Bardelli, Alberto, Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Zhang, Lin
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC534714/
https://ncbi.nlm.nih.gov/pubmed/15557007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403405101
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