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SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

Nonsteroidal antiinflammatory drugs (NSAIDs) form a paradigm for the chemoprevention of cancer, preventing colonic tumor progression in both experimental animals and humans. However, the mechanisms underlying the antineoplastic effects of NSAIDs are currently unclear. We found that the mitochondrial...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Kohli, Manu, Yu, Jian, Seaman, Craig, Bardelli, Alberto, Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Zhang, Lin
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC534714/
https://ncbi.nlm.nih.gov/pubmed/15557007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403405101
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