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SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

Nonsteroidal antiinflammatory drugs (NSAIDs) form a paradigm for the chemoprevention of cancer, preventing colonic tumor progression in both experimental animals and humans. However, the mechanisms underlying the antineoplastic effects of NSAIDs are currently unclear. We found that the mitochondrial...

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Detalles Bibliográficos
Main Authors: Kohli, Manu, Yu, Jian, Seaman, Craig, Bardelli, Alberto, Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Zhang, Lin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC534714/
https://ncbi.nlm.nih.gov/pubmed/15557007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403405101
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