SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

Nonsteroidal antiinflammatory drugs (NSAIDs) form a paradigm for the chemoprevention of cancer, preventing colonic tumor progression in both experimental animals and humans. However, the mechanisms underlying the antineoplastic effects of NSAIDs are currently unclear. We found that the mitochondrial...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

I whakaputaina i:	Proc Natl Acad Sci U S A
Ngā kaituhi matua:	Kohli, Manu, Yu, Jian, Seaman, Craig, Bardelli, Alberto, Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Zhang, Lin
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	National Academy of Sciences 2004
Ngā marau:	Biological Sciences
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534714/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15557007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403405101
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!