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A Dual Pathogenic Mechanism Links Tau Acetylation to Sporadic Tauopathy
Tau acetylation has recently emerged as a dominant post-translational modification (PTM) in Alzheimer’s disease (AD) and related tauopathies. Mass spectrometry studies indicate that tau acetylation sites cluster within the microtubule (MT)-binding region (MTBR), suggesting acetylation could regulate...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347034/ https://ncbi.nlm.nih.gov/pubmed/28287136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44102 |
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