Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members

Lysine acetylation has emerged as a dominant post-translational modification (PTM) regulating tau proteins in Alzheimer’s disease (AD) and related tauopathies. Mass spectrometry studies indicate that tau acetylation sites cluster within the microtubule-binding region (MTBR), a region that is highly...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hwang, Andrew W., Trzeciakiewicz, Hanna, Friedmann, Dave, Yuan, Chao-Xing, Marmorstein, Ronen, Lee, Virginia M. Y., Cohen, Todd J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176320/
https://ncbi.nlm.nih.gov/pubmed/28002468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168913
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