Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes

Recent studies underscore the role of the microenvironment in therapy resistance of chronic myeloid leukemia (CML) cells and leukemia progression. We previously showed that sustained mild activation of endoplasmic reticulum (ER) stress in CML cells supports their survival and resistance to chemother...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Podszywalow-Bartnicka, Paulina, Cmoch, Anna, Wolczyk, Magdalena, Bugajski, Lukasz, Tkaczyk, Marta, Dadlez, Michal, Nieborowska-Skorska, Margaret, Koromilas, Antonis E., Skorski, Tomasz, Piwocka, Katarzyna
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346746/
https://ncbi.nlm.nih.gov/pubmed/27802179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12941
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