Stimulators of Mineralization Limit the Invasive Phenotype of Human Osteosarcoma Cells by a Mechanism Involving Impaired Invadopodia Formation

BACKGROUND: Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with their ability to form invadopodia (structures specialized in extracellular matrix proteolysis). RESULTS: In this study, we tested th...

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Autors principals: Cmoch, Anna, Podszywalow-Bartnicka, Paulina, Palczewska, Malgorzata, Piwocka, Katarzyna, Groves, Patrick, Pikula, Slawomir
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196965/
https://ncbi.nlm.nih.gov/pubmed/25314307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109938
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