Stimulators of Mineralization Limit the Invasive Phenotype of Human Osteosarcoma Cells by a Mechanism Involving Impaired Invadopodia Formation

BACKGROUND: Osteosarcoma (OS) is a highly aggressive bone cancer affecting children and young adults. Growing evidence connects the invasive potential of OS cells with their ability to form invadopodia (structures specialized in extracellular matrix proteolysis). RESULTS: In this study, we tested th...

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Bibliographic Details
Main Authors: Cmoch, Anna, Podszywalow-Bartnicka, Paulina, Palczewska, Malgorzata, Piwocka, Katarzyna, Groves, Patrick, Pikula, Slawomir
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4196965/
https://ncbi.nlm.nih.gov/pubmed/25314307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109938
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