Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes

Recent studies underscore the role of the microenvironment in therapy resistance of chronic myeloid leukemia (CML) cells and leukemia progression. We previously showed that sustained mild activation of endoplasmic reticulum (ER) stress in CML cells supports their survival and resistance to chemother...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Podszywalow-Bartnicka, Paulina, Cmoch, Anna, Wolczyk, Magdalena, Bugajski, Lukasz, Tkaczyk, Marta, Dadlez, Michal, Nieborowska-Skorska, Margaret, Koromilas, Antonis E., Skorski, Tomasz, Piwocka, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346746/
https://ncbi.nlm.nih.gov/pubmed/27802179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12941
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