Increased phosphorylation of eIF2α in chronic myeloid leukemia cells stimulates secretion of matrix modifying enzymes

Recent studies underscore the role of the microenvironment in therapy resistance of chronic myeloid leukemia (CML) cells and leukemia progression. We previously showed that sustained mild activation of endoplasmic reticulum (ER) stress in CML cells supports their survival and resistance to chemother...

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Vydáno v:Oncotarget
Hlavní autoři: Podszywalow-Bartnicka, Paulina, Cmoch, Anna, Wolczyk, Magdalena, Bugajski, Lukasz, Tkaczyk, Marta, Dadlez, Michal, Nieborowska-Skorska, Margaret, Koromilas, Antonis E., Skorski, Tomasz, Piwocka, Katarzyna
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346746/
https://ncbi.nlm.nih.gov/pubmed/27802179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12941
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