Metformin treatment reduces temozolomide resistance of glioblastoma cells

It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM). However, the molecular mechanism underlying how metformin exerts its anti-cancer effects remains elusive. We used a combined experimental...

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Vydáno v:Oncotarget
Hlavní autoři: Yang, Seung Ho, Li, Shenglan, Lu, Guangrong, Xue, Haipeng, Kim, Dong H., Zhu, Jay-Jiguang, Liu, Ying
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346677/
https://ncbi.nlm.nih.gov/pubmed/27791206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12859
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