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Metformin treatment reduces temozolomide resistance of glioblastoma cells

It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM). However, the molecular mechanism underlying how metformin exerts its anti-cancer effects remains elusive. We used a combined experimental...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Yang, Seung Ho, Li, Shenglan, Lu, Guangrong, Xue, Haipeng, Kim, Dong H., Zhu, Jay-Jiguang, Liu, Ying
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346677/
https://ncbi.nlm.nih.gov/pubmed/27791206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12859
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