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Metformin treatment reduces temozolomide resistance of glioblastoma cells

It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM). However, the molecular mechanism underlying how metformin exerts its anti-cancer effects remains elusive. We used a combined experimental...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Yang, Seung Ho, Li, Shenglan, Lu, Guangrong, Xue, Haipeng, Kim, Dong H., Zhu, Jay-Jiguang, Liu, Ying
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346677/
https://ncbi.nlm.nih.gov/pubmed/27791206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12859
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