Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor survival. Cytoreduction in association with radiotherapy and temozolomide (TMZ) is the standard therapy, but response is heterogeneous and life expectancy is limited. The combined use of chemotherapeutic agents with d...

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發表在:Oncotarget
Main Authors: Valtorta, Silvia, Lo Dico, Alessia, Raccagni, Isabella, Gaglio, Daniela, Belloli, Sara, Politi, Letterio S, Martelli, Cristina, Diceglie, Cecilia, Bonanomi, Marcella, Ercoli, Giulia, Vaira, Valentina, Ottobrini, Luisa, Moresco, Rosa Maria
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762574/
https://ncbi.nlm.nih.gov/pubmed/29348889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23028
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