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Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models
Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor survival. Cytoreduction in association with radiotherapy and temozolomide (TMZ) is the standard therapy, but response is heterogeneous and life expectancy is limited. The combined use of chemotherapeutic agents with d...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5762574/ https://ncbi.nlm.nih.gov/pubmed/29348889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23028 |
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