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Hypoxia-Inducible Factor-1α Activity as a Switch for Glioblastoma Responsiveness to Temozolomide

RATIONALE: The activity of the transcription factor, hypoxia-inducible factor (HIF)-1α, is a common driver of a number of the pathways involved in the aggressiveness of glioblastomas (GBMs), and it has been suggested that the reduction in this activity observed, soon after the administration of temo...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Lo Dico, Alessia, Martelli, Cristina, Diceglie, Cecilia, Lucignani, Giovanni, Ottobrini, Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036118/
https://ncbi.nlm.nih.gov/pubmed/30013951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00249
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