Metformin treatment reduces temozolomide resistance of glioblastoma cells

It has been reported that metformin acts synergistically with temozolomide (TMZ) to inhibit proliferation of glioma cells including glioblastoma multiforme (GBM). However, the molecular mechanism underlying how metformin exerts its anti-cancer effects remains elusive. We used a combined experimental...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Yang, Seung Ho, Li, Shenglan, Lu, Guangrong, Xue, Haipeng, Kim, Dong H., Zhu, Jay-Jiguang, Liu, Ying
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346677/
https://ncbi.nlm.nih.gov/pubmed/27791206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12859
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