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EXTH-67. HIGH-DOSE METFORMIN PLUS TEMOZOLOMIDE SHOWS INCREASED ANTI-TUMOR EFFECTS IN GLIOBLASTOMA IN VITRO AND IN VIVO COMPARED WITH MONOTHERAPY
Glioblastoma (GBM) is one of the most aggressive cancers and the most common primary brain tumor. Although concomitant chemoradiotherapy using temozolomide (TMZ) has been established as the standard therapy, the median survival is approximately 14 months. Metformin, an anti-diabetic agent, has been...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6216225/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy148.414 |
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