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Combinatorial codon-based amino acid substitutions

Twenty Fmoc-protected trinucleotide phosphoramidites representing a complete set of codons for the natural amino acids were chemically synthesized for the first time. A pool of these reagents was incorporated into oligonucleotides at substoichiometric levels to generate two libraries of variants tha...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Yáñez, Jorge, Argüello, Martha, Osuna, Joel, Soberón, Xavier, Gaytán, Paul
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15537836/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnh156
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