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RNA aptamers selected against the receptor activator of NF-κB acquire general affinity to proteins of the tumor necrosis factor receptor family

The receptor activator of NF-κB (RANK) is a member of the tumor necrosis factor (TNF) receptor family and acts to cause osteoclastgenesis through the interaction with its ligand, RANKL. We isolated RNA aptamers with high affinity to human RANK by SELEX. Sequence and mutational analysis revealed that...

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Bibliografski detalji
Glavni autori: Mori, Tadashi, Oguro, Akihiro, Ohtsu, Takashi, Nakamura, Yoshikazu
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC534629/
https://ncbi.nlm.nih.gov/pubmed/15562003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh949
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