Reproduction and In-Depth Evaluation of Genome-Wide Association Studies and Genome-Wide Meta-analyses Using Summary Statistics

In line with open-source genetics, we report a novel linear regression technique for genome-wide association studies (GWAS), called Open GWAS algoriTHm (OATH). When individual-level data are not available, OATH can not only completely reproduce reported results from an experimental model, but also r...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:G3 (Bethesda)
Main Authors: Niu, Yao-Fang, Ye, Chengyin, He, Ji, Han, Fang, Guo, Long-Biao, Zheng, Hou-Feng, Chen, Guo-Bo
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2017
Teme:
Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345724/
https://ncbi.nlm.nih.gov/pubmed/28122950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.038877
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