Empirical power of very rare variants for common traits and disease: results from sanger sequencing 1998 individuals

Por Ladouceur, Martin, Zheng, Hou-Feng, Greenwood, Celia M T, Richards, J Brent
Publicado em 2013

A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects

Por Sun, Jianping, Oualkacha, Karim, Forgetta, Vincenzo, Zheng, Hou-Feng, Brent Richards, J, Ciampi, Antonio, Greenwood, Celia MT
Publicado no Eur J Hum Genet (2016)

Performance of Genotype Imputation for Low Frequency and Rare Variants from the 1000 Genomes

Por Zheng, Hou-Feng, Rong, Jing-Jing, Liu, Ming, Han, Fang, Zhang, Xing-Wei, Richards, J. Brent, Wang, Li
Publicado no PLoS One (2015)

Reproduction and In-Depth Evaluation of Genome-Wide Association Studies and Genome-Wide Meta-analyses Using Summary Statistics

Por Niu, Yao-Fang, Ye, Chengyin, He, Ji, Han, Fang, Guo, Long-Biao, Zheng, Hou-Feng, Chen, Guo-Bo
Publicado no G3 (Bethesda) (2017)

Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation

Por Sun, Jianping, Oualkacha, Karim, Forgetta, Vincenzo, Zheng, Hou-Feng, Richards, J. Brent, Evans, Daniel S., Orwoll, Eric, Greenwood, Celia M. T.
Publicado no Sci Rep (2018)

Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study

Por Trajanoska, Katerina, Morris, John A, Oei, Ling, Zheng, Hou-Feng, Evans, David M, Kiel, Douglas P, Ohlsson, Claes, Richards, J Brent, Rivadeneira, Fernando
Publicado no BMJ (2018)

Genetic interactions affecting human gene expression identified by variance association mapping

Por Brown, Andrew Anand, Buil, Alfonso, Viñuela, Ana, Lappalainen, Tuuli, Zheng, Hou-Feng, Richards, J Brent, Small, Kerrin S, Spector, Timothy D, Dermitzakis, Emmanouil T, Durbin, Richard
Publicado em 2014

A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples

Por Chou, Wen-Chi, Zheng, Hou-Feng, Cheng, Chia-Ho, Yan, Han, Wang, Li, Han, Fang, Richards, J. Brent, Karasik, David, Kiel, Douglas P., Hsu, Yi-Hsiang
Publicado no Sci Rep (2016)

Comprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-Analysis

Por Zhu, Xiao-Wei, Wang, Yong, Wei, Yi-Hua, Zhao, Pian-Pian, Wang, Xiao-Bo, Rong, Jing-Jing, Zhong, Wen-Ying, Zhang, Xing-Wei, Wang, Li, Zheng, Hou-Feng
Publicado no Sci Rep (2016)

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

Por Mullin, Benjamin H., Walsh, John P., Zheng, Hou-Feng, Brown, Suzanne J., Surdulescu, Gabriela L., Curtis, Charles, Breen, Gerome, Dudbridge, Frank, Richards, J. Brent, Spector, Tim D., Wilson, Scott G.
Publicado no BMC Genomics (2016)

Effect of CD14 polymorphisms on the risk of cardiovascular disease: evidence from a meta-analysis

Por Xu, Jin-Jian, Liu, Ke-Qi, Ying, Zhi-Min, Zhu, Xiao-Wei, Xu, Xue-Jin, Zhao, Pian-Pian, Bai, Wei-Yang, Qiu, Mo-Chang, Zhang, Xing-Wei, Zheng, Hou-Feng
Publicado no Lipids Health Dis (2019)

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Por Huang, Jie, Howie, Bryan, McCarthy, Shane, Memari, Yasin, Walter, Klaudia, Min, Josine L., Danecek, Petr, Malerba, Giovanni, Trabetti, Elisabetta, Zheng, Hou-Feng, Gambaro, Giovanni, Richards, J. Brent, Durbin, Richard, Timpson, Nicholas J., Marchini, Jonathan, Soranzo, Nicole
Publicado no Nat Commun (2015)

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

Por Mullin, Benjamin H., Zhao, Jing Hua, Brown, Suzanne J., Perry, John R.B., Luan, Jian'an, Zheng, Hou-Feng, Langenberg, Claudia, Dudbridge, Frank, Scott, Robert, Wareham, Nick J., Spector, Tim D., Richards, J. Brent, Walsh, John P., Wilson, Scott G.
Publicado no Hum Mol Genet (2017)

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based...

Por Wood, Andrew R., Perry, John R. B., Tanaka, Toshiko, Hernandez, Dena G., Zheng, Hou-Feng, Melzer, David, Gibbs, J. Raphael, Nalls, Michael A., Weedon, Michael N., Spector, Tim D., Richards, J. Brent, Bandinelli, Stefania, Ferrucci, Luigi, Singleton, Andrew B., Frayling, Timothy M.
Publicado em 2013

Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes

Por Ruth, Katherine S, Campbell, Purdey J, Chew, Shelby, Lim, Ee Mun, Hadlow, Narelle, Stuckey, Bronwyn GA, Brown, Suzanne J, Feenstra, Bjarke, Joseph, John, Surdulescu, Gabriela L, Zheng, Hou Feng, Richards, J Brent, Murray, Anna, Spector, Tim D, Wilson, Scott G, Perry, John RB
Publicado no Eur J Hum Genet (2016)

Meta-Analysis of Genome-Wide Studies Identifies MEF2C SNPs Associated with Bone Mineral Density at Forearm

Por Zheng, Hou-Feng, Duncan, Emma, Yerges-Armstrong, Laura M., Eriksson, Joel, Bergström, Ulrica, Leo, Paul J., Leslie, William D., Goltzman, David, Blangero, John, Hanley, David A., Carless, Melanie A., Streeten, Elizabeth A., Lorentzon, Mattias, Brown, Matthew A., Spector, Tim D., Pettersson-Kymmer, Ulrika, Ohlsson, Claes, Mitchell, Braxton D., Richards, J. Brent
Publicado em 2013

Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

Por Keildson, Sarah, Fadista, Joao, Ladenvall, Claes, Hedman, Åsa K., Elgzyri, Targ, Small, Kerrin S., Grundberg, Elin, Nica, Alexandra C., Glass, Daniel, Richards, J. Brent, Barrett, Amy, Nisbet, James, Zheng, Hou-Feng, Rönn, Tina, Ström, Kristoffer, Eriksson, Karl-Fredrik, Prokopenko, Inga, Spector, Timothy D., Dermitzakis, Emmanouil T., Deloukas, Panos, McCarthy, Mark I., Rung, Johan, Groop, Leif, Franks, Paul W., Lindgren, Cecilia M., Hansson, Ola
Publicado em 2014

A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response

Por Lyu, Xiao‐Ming, Zhu, Xiao‐Wei, Zhao, Manli, Zuo, Xian‐Bo, Huang, Zhong‐Xi, Liu, Xiao, Jiang, Tao, Yang, Xue‐Xi, Li, Xin, Long, Xiao‐Bing, Wang, Jian‐Guo, Li, Jin‐Bang, Han, Ming‐Yu, Wang, Shuang, Liu, Teng‐Fei, Zhang, Bo, Sun, Tao, Cheng, Zhi, Qiu, Mo‐Chang, Dong, Lei, Zheng, Lu, Zhang, Long‐Cheng, Wang, Jia‐Hong, Wei, Gan‐Guan, Yao, Kaitai, Wang, Qian, Zheng, Hou‐Feng, Li, Xin
Publicado no Cancer Med (2018)

Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus

Por Medina-Gomez, Carolina, Kemp, John P., Estrada, Karol, Eriksson, Joel, Liu, Jeff, Reppe, Sjur, Evans, David M., Heppe, Denise H. M., Vandenput, Liesbeth, Herrera, Lizbeth, Ring, Susan M., Kruithof, Claudia J., Timpson, Nicholas J., Zillikens, M. Carola, Olstad, Ole K., Zheng, Hou-Feng, Richards, J. Brent, St. Pourcain, Beate, Hofman, Albert, Jaddoe, Vincent W. V., Smith, George Davey, Lorentzon, Mattias, Gautvik, Kaare M., Uitterlinden, André G., Brommage, Robert, Ohlsson, Claes, Tobias, Jonathan H., Rivadeneira, Fernando
Publicado em 2012

Systemic evaluation of the relationship between psoriasis, psoriatic arthritis and osteoporosis: observational and mendelian randomization study

Por Xia, Jiangwei, Xie, Shu-Yang, Liu, Ke-Qi, Xu, Lin, Zhao, Pian-Pian, Gai, Si-Rui, Guan, Peng-Lin, Zhao, Jin-Qiu, Zhu, Yan-Ping, Tsoi, Lam C., Stuart, Philip E., Nair, Rajan P., Yang, Han-Qi, Liao, Yu-Ting, Mao, Kaijing, Qiu, Mo-Chang, Ying, Zhi-Min, Hu, Bin, Yang, Zhi-Hua, Bai, Wei-Yang, Zhu, Xiao-Wei, Cong, Pei-Kuan, Elder, James T., Ye, Zhao-Ming, Wang, Bin, Zheng, Hou-Feng
Publicado no Ann Rheum Dis (2020)