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Genetic interactions affecting human gene expression identified by variance association mapping

Non-additive interaction between genetic variants, or epistasis, is a possible explanation for the gap between heritability of complex traits and the variation explained by identified genetic loci. Interactions give rise to genotype dependent variance, and therefore the identification of variance qu...

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書誌詳細
主要な著者: Brown, Andrew Anand, Buil, Alfonso, Viñuela, Ana, Lappalainen, Tuuli, Zheng, Hou-Feng, Richards, J Brent, Small, Kerrin S, Spector, Timothy D, Dermitzakis, Emmanouil T, Durbin, Richard
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017648/
https://ncbi.nlm.nih.gov/pubmed/24771767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01381
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