Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies

BACKGROUND: RNA sequencing (RNA-seq) is the current gold-standard method to quantify gene expression for expression quantitative trait locus (eQTL) studies. However, a potential caveat in these studies is that RNA-seq reads carrying the non-reference allele of variant loci can have lower probability...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Panousis, Nikolaos I, Gutierrez-Arcelus, Maria, Dermitzakis, Emmanouil T, Lappalainen, Tuuli
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4212091/
https://ncbi.nlm.nih.gov/pubmed/25239376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0467-2
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