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Allelic mapping bias in RNA-sequencing is not a major confounder in eQTL studies
BACKGROUND: RNA sequencing (RNA-seq) is the current gold-standard method to quantify gene expression for expression quantitative trait locus (eQTL) studies. However, a potential caveat in these studies is that RNA-seq reads carrying the non-reference allele of variant loci can have lower probability...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4212091/ https://ncbi.nlm.nih.gov/pubmed/25239376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-014-0467-2 |
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