Expression estimation and eQTL mapping for HLA genes with a personalized pipeline

The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little information exists about the regulatio...

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Опубликовано в: :PLoS Genet
Главные авторы: Aguiar, Vitor R. C., César, Jônatas, Delaneau, Olivier, Dermitzakis, Emmanouil T., Meyer, Diogo
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2019
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497317/
https://ncbi.nlm.nih.gov/pubmed/31009447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008091
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