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Expression estimation and eQTL mapping for HLA genes with a personalized pipeline

The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little information exists about the regulatio...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Aguiar, Vitor R. C., César, Jônatas, Delaneau, Olivier, Dermitzakis, Emmanouil T., Meyer, Diogo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497317/
https://ncbi.nlm.nih.gov/pubmed/31009447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008091
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