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Expression estimation and eQTL mapping for HLA genes with a personalized pipeline

The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little information exists about the regulatio...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Aguiar, Vitor R. C., César, Jônatas, Delaneau, Olivier, Dermitzakis, Emmanouil T., Meyer, Diogo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497317/
https://ncbi.nlm.nih.gov/pubmed/31009447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008091
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