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Testing Genetic Pleiotropy with GWAS Summary Statistics for Marginal and Conditional Analyses

There is growing interest in testing genetic pleiotropy, which is when a single genetic variant influences multiple traits. Several methods have been proposed; however, these methods have some limitations. First, all the proposed methods are based on the use of individual-level genotype and phenotyp...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Deng, Yangqing, Pan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714448/
https://ncbi.nlm.nih.gov/pubmed/28971959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300347
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